If R2 misses third base but scores, what can the defense still do?

When a runner misses a base and subsequently scores, the defense retains the right to appeal the missed base. In this situation, even though R2 has crossed home plate, the defense can still appeal that R2 did not legally touch third base. If the appeal is successful, the run would be nullified because R2 failed to properly complete the base-running responsibilities.

The option that states the defense cannot appeal after the run scores is incorrect because appeals can still be made regardless of the scoring status as long as the appeal is made within the proper time frame. The idea that the defense can only appeal if R2 stops at home is misleading since appeals can occur after a runner has scored under specific circumstances. Finally, while an appeal must generally be made before the next pitch is thrown, the requirement doesn't limit the appeal to a specific event like a batter stepping up. Therefore, the correct understanding is that the defense has the ability to appeal R2’s missed third base even after the run has scored.